It’s Zack and Cody’s first day at a new school, and they are trying to make friends. But once the word gets out that they live in the Tipton hotel, the cool kids start to hang out with them. But soon Zack and Cody realize who their real friends are. Also, London teaches Maddie how to ask Lance, the lifeguard out, and Maddie teaches London math.

A beauty pageant is being held at the Tipton hotel, that is giving out a prize of money. Cody enters when he sees a girl that he likes, and Zack wants him to enter so they can win the money and get new bikes.

A cute, rich boy checks into the Tipton hotel, and Maddie starts to like him, but realizes she has no chance with him, because she is not rich. Zack and Cody help her pretend that she is rich. Once he finds out that Maddie is not rich, he still does not care.

When a hotel inspector comes to the Tipton, and Mr. Mosbey give the twins Red Sox tickets. But when Zack and Cody’s science fair rats run loose, Mr. Mosbey gets blamed.

The twins get grounded in their hotel room on the 23rd floor after they get in trouble for running around and causing havoc in the hotel. But when they find out about a $20,000 kiss taking place in the hotel, they decide to get a picture of it, so thy won't be burdens anymore.

Carey gets a secret admirer, and Zack and Cody try to find out who. When they set her up with the wrong guy, they have to find the real guy. Mr. Tipton is coming soon, and London and Mr. Moseby are anticipating his arrival.

Zack helps Max in a dance competition. This makes Cody wonder what he is good at. But when Zack injures himself, Cody has to take his place.

Maddie organizes her school prom to impress a boy, but when he has a date to prom, she goes with Zack instead. Cody decides to become a mime.

Zack and Cody enter the Battle of the Bands that is held at the Tipton. Zack and Cody have some differences about their band, so they break up the band. Once it comes down to it, they realize that they work better together that apart.Cody gets mad when Zack starts playing around and Cody leaves the band, who made his own band with Muriel and Arwin.

When Cody goes to math camp, Zack thinks that it will be great, but soon he realizes that he misses Cody. Also, London learns how to drive with the help of Mr. Moseby.

There are jewel thieves in the Tipton, and once Esteban gets blamed, Zack and Cody have to clean his name.

The twins go looking for a treasure at the Tipton, but soon everybody joins in on the hunt.

When London's father makes a bad investment, the Tiptons go broke, and she is forced to live with Maddie and her family. Also, Zack and Cody are unsure if they are really them, or if they were mixed up at birth.

London gets a crush on the rival hotel, run by Ilsa, owner’s son. Also, Zack and Cody bake cookies for a ball in the Tipton.

London spreads a rumor about Maddie, and Lance the lifeguard. Then Maddie accidentally spreads one about London, which hurts her image. Also, Zack has to take Cody’s spot in an interview for a week in Washington.

Carey needs some time away from the boys, so she arranges for Mr. Moseby to take the boys to a baseball game, but when Mr. Moseby catches the winning ball for the Yankees, he becomes the most hated man in Boston.

Jesse McCartney checks into the Tipton, and London, Maddie and Zack break into his room. Also, Cody enters a science fair, with the help of Arwin.

When the twins hear about a ghost in Suite 613, they do anything to see her. In the end, Zack finds out the ghost was all a trick by Cody with the help of Maddie and London.

After getting bad grades in school, Zack decides that if he pretends to be dyslexic he will get better grades. Meanwhile, London beats Maddie in chess, which drives her crazy.

The boys receive a visit from their mostly absent rock-musician father, who lets Zack and Cody do things that their mom would never allow. When Zack gets into an argument with Carey about his homework, he decides to leave the comforts of home to stow away on his dad's tour bus.

Zack, Cody and the gang get snowed in at the hotel. While there, Kurt and Carey spend time together singing and playing music, which gives Cody the wrong impression that his parents are getting back together.

After winning a basketball game, Max kisses Zack, accidentally. After that, things become awkward between Zack and Max. In order to clear the air, Zack decides to ask Max out, which does not go as he planned. Also, Maddie must help London stop shopping; otherwise London’s father will disinherit her.

Zack and Cody have a school project to help out their community with some form of volunteering. Meanwhile, Maddie and London compete in a fashion show to appear on the cover of Teen Trends.

Cody gains an admirer after going on a school trip, for he was the only one nice to her, but Cody does not want her to be his girlfriend so he tries to make her not like him by using Zack, this makes the girl love Zack instead, so they have to come up with a new plan. Also, Maddie brings her dog Scamps to work, and Scamps makes a new dog friend, a rich dog friend.

A commercial is being shot at the Tipton. The only problem is, the director resents Carey for once standing him up in the past, London is using her heiress status to be the star, and everyone has star syndrome due to all the publicity.

In the season finale, Prince Sanjei comes to the Tipton as part of a royal visit, but when he tells Zack and Cody he wants to try being a regular kid, Cody poses as him while Zack takes Sanjei to the mall. Meanwhile, London thinks she saw a UFO, so she invites Maddie over to stay up and look for one, although Maddie goes along with it just for the comforts of being rich.